Stern has never been shy about proclaiming West his favorite rock guitarist, and their friendship has produced countless hours of entertaining radio banter over the years, but this week’s appearance was something different. Although Stern’s show is only available to SiriusXM subscribers, you can listen to a clip from his appearance below.

His wife Jenni explained in a press statement that: “The doctors tried for two days to save it to no avail. The decision to amputate was one that was necessary to save his life as the infection was spreading throughout his body.”

Roger Daltrey, Mark Farner, Leslie West and AC/DC bassist Cliff Williams are among the artists set to perform at a benefit show at New York’s B.B. King’s Blues Club on Monday (Jan. 17). Bad Company drummer Simon Kirke, 3 Doors Down, Kip Winger and others are also scheduled to appear. Proceeds from ticket sales will go toward the medical expenses of Farner’s 21-year-old son, Jesse. This past summer, Jesse Farner suffered a serious neck injury resulting from a fall, and he remains in intensive care.